Medical Technology Licensure Examination

Urine

Composition: 95-97% water, 3-5% solids Sample should be delivered and tested in the laboratory within 2 hours As soon as urine is voided, changes occur TOTAL SOLIDS IN 24 HOURS: 60 grams MAJOR ORGANIC SUBS: UREA MAJOR INORGANIC SUBS:Cl- > Na+ > K CHANGES IN UNPRESERVED URINE INCREASED REASON Odor Urea ➡ ammonia due to bacterial …

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Renal Function

RENAL FUNCTIONS RENAL BLOOD FLOW  GLOMERULAR FILTRATION  TUBULAR REABSORPTION  TUBULAR SECRETION Urine Formation Glomerulus 🡆 PCT 🡆 Loop of Henle 🡆 DCT 🡆 CD 🡆 Calyx 🡆 Renal Pelvis I. Renal Blood Flow 1. Renal artery Supplies 25% of blood to kidney (blood in) 2. Afferent arteriole Entry of blood (to the nephrons) 3. Glomerulus …

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Nephron

Functional unit of kidneys 1 – 1.5 million EACH kidney Composed of glomerulus and tubules 2 types of nephrons: Cortical nephron: 85% (majority) For tubular reabsorption and removal of waste products, Juxtamedullary nephron: For the concentration of urine GLOMERULUS  Consists of a coil approx. of 8 capillary lobes  Within Bowman’s capsule  NONSELECTIVE FILTER (substances <70k …

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Protozoans

E. histolytica Transmission Fecal-oral Morphology Oocyst  Troph: bullseye shaped nucleus; RBC in cytoplasm Clinical Findings Asymptomatic carrier Bloody diarrhea Liver abscess Diagnosis Fecal smear Serology CT Scan G. lamblia Transmission Fecal-oral Morphology Oocyst  Flagellated trophozoite Clinical Findings Foul smelling,greasy diarrhea Diagnosis Fecal smear Immunoassay Isospora spp. Transmission Fecal-oral Morphology Oocyst Clinical Findings Severe diarrhea and …

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Trematodes

Known as flukes  Requires 2 intermediate hosts exc. Schistosomes  1st – snail  2nd : FISH H. heterophyes,C. sinensisO. felineus CRAB P. westermani PLANT F. hepaticaF. giganticaF. buski SNAIL E. ilocanum BLOOD FLUKES  S. japonicum – small lateral knob; oriental blood fluke; katayama syndrome; swimmer’s itch; snail fever  S. mansoni – prominent lateral; smallest blood …

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Cestodes

Tapeworm; flat and ribbon-like  Hermaphrodite; lack digestive organs Body  Scolex (head)  Neck (region of growth)  Proglottids (strobila) Taenia spp   Taenia solium Taenia saginata Common name Pork Tapeworm Beef tapeworm Intermediate host Pig; man Cattle Scolex w/ rostellum armedwith 2 rows of large &small hooklets No rostellar hooks4 prominent acetabula Length <7 meters <25 meters …

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Blood & Tissue Nematodes

SUBCUTANEOUS  Loa loa  Mansonella streptocerca  Onchocerca volvulus SEROUS CAVITY  Mansonella spp. LYMPHATIC  Wuchereria bancrofti  Brugia malayi   W. bancrofti B. malayi Mean length (um) 290 222 Cephalic space:breadth 1:1 2:1 Sheath in giemsa Unstained Pink Nuclei Regularly spaced;separate Irregularly spaced;overlapping Tail Single row of nuclei;does not reach tail end Single row of nucleireaches the tail …

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Nematodes

Characteristics  Cylindrical, elongated, & bilaterally symmetrical  Anterior end equipped with hook, teeth, plates and papillae  Alimentary tract is simple, extending from mouth to anus. NO CIRCULATORY SYSTEM UNHOLY THREE Hookworm Ascaris lumbricoides Trichuris trichiura HEART-LUNG MIGRATION Ascaris lumbricoides Strongyloides stercoralis Hookworm SMALL INTESTINE Capillaria philippinensis Hookworm Ascaris lumbricoides Trichuris trichiura Strongyloides stercoralis LARGE INTESTINE Enterobius …

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Mycobacteria

Slender, rod-shaped (0.2- 0.6 um x 1- 10um in size)  Nonmotile; non-spore formers  Strictly aerobic  Increased CO2 – enhances growth RAPID GROWERS  Grows in simple media  Grows 2-3 days  20-40°C DISEASE-ASSOCIATED MYCOBACTERIA  Requires 2-6 weeks  Requires complex media  Has specific optimal temp. MTB COMPLEX  M. microti – TB in immunocompetent and compromised  M. africanum – …

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